Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22435208 | 0.94 | FKBP5 (0.34) | ITGB3ITGB1ITGAVITGA4 | |
| SCHEMBL16107849 | 0.84 | — | — | |
| SCHEMBL12963772 | 0.84 | — | — | |
| SCHEMBL16107526 | 0.84 | — | — | |
| SCHEMBL19012984 | 0.83 | OR51E2 (0.31) | OR51E2 | |
| SCHEMBL22435291 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL4648884 | 0.78 | ITGB3 (0.43) | OR51E2ITGB3ITGB1ITGAVITGA4 | |
| SCHEMBL18796727 | 0.78 | ITGB3 (0.43) | OR51E2ITGB3ITGB1ITGAVITGA4 | |
| SCHEMBL13545399 | 0.76 | ITGB3 (0.42) | OR51E2ITGB3ITGB1ITGAVITGA4 | |
| SCHEMBL22435204 | 0.74 | FKBP5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185606-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2020-09-17 | — | — | WO | disclosed |