SCHEMBL22436

SCHEMBL22436

CCC(C(=O)ON1C(=O)CCC1=O)(c1ccccc1)N1C(=O)C=CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 4/20 0.36
CHRM2 P08172 3/20 0.36
CHRM1 P11229 3/20 0.36
MLNR O43193 1/20 0.36
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HRH1 P35367 1/20 0.36
OPRM1 P35372 1/20 0.36
DRD3 P35462 1/20 0.36
OPRK1 P41145 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1C Q13936 1/20 0.36
MGLL Q99685 2/20 0.33
GAA P10253 1/20 0.33
ALOX12 P18054 1/20 0.33
PARL Q9H300 1/20 0.33
RAB9A P51151 1/20 0.32
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7387232 0.79 GAA (0.44) CHRM3CHRM2CHRM1MLNRHTR2A
SCHEMBL1824378 0.78 CYP2C19 (0.37) CHRM3CHRM2CHRM1MLNRHTR2A
SCHEMBL16628550 0.76 MAPT (0.43) CHRM3CHRM2CHRM1MLNRHTR2A
SCHEMBL8102600 0.73 PARL (0.42) CHRM3CHRM2CHRM1MGLLALOX12
SCHEMBL3686239 0.71 PARL (0.40) CHRM3CHRM2CHRM1MGLLALOX12
SCHEMBL22137026 0.70
SCHEMBL19982355 0.70
SCHEMBL7166115 0.69 PARL (0.36) CHRM3MGLLALOX12PARLRIPK1
SCHEMBL18849697 0.69 MEN1 (0.31) MGLL
SCHEMBL31099227 0.69 KCNN4 (0.38) MGLLALOX12PARLKCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2609119-B1 CHITINOUS POLYSACCHARIDE ANTIGEN BINDING PROTEINS AGROSAVFE N V (BE) 2017-10-18 EP disclosed
EP-2609115-B1 COMPOSITIONS FOR SEED TREATMENT AGROSAVFE N V (BE) 2017-05-31 EP disclosed
US-9516879-B2 Chitinous polysaccharide antigen-binding proteins AGROSAVFE N.V. (BE) 2016-12-13 US disclosed
US-9380781-B2 Compositions for seed treatment AGROSAVFE N.V. (BE) 2016-07-05 US disclosed
US-20130227747-A1 CHITINOUS POLYSACCHARIDE ANTIGEN-BINDING PROTEINS AGROSAVFE N.V. (BE) 2013-08-29 US disclosed
US-20130225403-A1 COMPOSITIONS FOR SEED TREATMENT AGROSAVFE N.V. (BE) 2013-08-29 US disclosed
EP-2609119-A1 CHITINOUS POLYSACCHARIDE ANTIGEN BINDING PROTEINS AGROSAVFE N.V. (BE) 2013-07-03 EP disclosed
EP-2609115-A1 COMPOSITIONS FOR SEED TREATMENT AGROSAVFE N.V. (BE) 2013-07-03 EP disclosed
WO-2012025619-A1 CHITINOUS POLYSACCHARIDE ANTIGEN BINDING PROTEINS VIB VZW (BE) 2012-03-01 WO disclosed
WO-2012025621-A1 COMPOSITIONS FOR SEED TREATMENT VIB VZW (BE) 2012-03-01 WO disclosed