Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PARL | Q9H300 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102600 | 0.83 | PARL (0.42) | ALDH1A1PARLCHRM3CHRM2CHRM1 | |
| SCHEMBL22436 | 0.79 | CHRM3 (0.36) | GAAPARLCHRM3CHRM2CHRM1 | |
| SCHEMBL3686239 | 0.77 | PARL (0.40) | ALDH1A1PARLCHRM3CHRM2CHRM1 | |
| SCHEMBL7166115 | 0.75 | PARL (0.36) | PARLCHRM3MGLLALOX12KCNN4 | |
| SCHEMBL31099227 | 0.74 | KCNN4 (0.38) | HDAC1PARLMGLLALOX12KCNN4 | |
| SCHEMBL705142 | 0.74 | KCNN4 (0.46) | GAARGS12APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL21447572 | 0.73 | ME2 (0.41) | ALDH1A1PARLCHRM3CHRM2CHRM1 | |
| SCHEMBL11044343 | 0.73 | MEN1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL19840559 | 0.73 | MAPT (0.31) | MGLL | |
| SCHEMBL8483586 | 0.73 | PIN1 (0.53) | ALDH1A1HDAC1CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | claimed |
| US-5281617-A | Enzyme inhibitor | CORTECH, INC. (US) | 1994-01-25 | — | — | US | disclosed |