SCHEMBL22436097

SCHEMBL22436097

FC(F)(F)CCSN1CCCC1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22436082 0.74
SCHEMBL18583119 0.65
SCHEMBL5311125 0.63 HRH3 (0.43)
SCHEMBL19881640 0.63 MGLL (0.43) MGLL
SCHEMBL575496 0.62
SCHEMBL21087526 0.62 MGLL (0.47) MGLL
SCHEMBL576316 0.62
SCHEMBL3239656 0.62 L3MBTL1 (0.35) MGLL
SCHEMBL7476173 0.62 HRH3 (0.48)
SCHEMBL18701472 0.62 MGLL (0.35) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020182159-A1 JAK KINASE INHIBITOR, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF IN FIELD OF MEDICINE 上海华汇拓医药科技有限公司 2020-09-17 WO disclosed