Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11639779 | 0.80 | CYP1A2 (0.48) | HRH3TAAR1CYP1A2CYP2A6 | |
| SCHEMBL9154608 | 0.78 | TAAR1 (0.47) | TAAR1 | |
| SCHEMBL11336831 | 0.78 | TAAR1 (0.47) | LOXL2TAAR1 | |
| SCHEMBL9150568 | 0.78 | ESR1 (0.55) | TAAR1 | |
| SCHEMBL31524115 | 0.78 | HRH3 (0.58) | HRH3LOXL2HTR2AABATTAAR1 | |
| SCHEMBL6312084 | 0.78 | HRH3 (0.58) | HRH3LOXL2HTR2AABATTAAR1 | |
| SCHEMBL430012 | 0.77 | SIGMAR1 (0.54) | MAOA | |
| SCHEMBL11127803 | 0.77 | ESR1 (0.59) | HTR2A | |
| SCHEMBL9149013 | 0.75 | CALM1 (0.58) | TAAR1 | |
| SCHEMBL394855 | 0.75 | HTR2A (0.61) | HRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710059-A1 | CLEAVABLE CONJUGATES OF TLR7/8 AGONIST COMPOUNDS, METHODS FOR PREPARATION, AND USES THEREOF | Dynavax Technologies Corporation (US) | 2020-09-23 | — | — | EP | disclosed |