Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22370558 | 1.00 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL31441479 | 0.94 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL31441492 | 0.94 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL17848607 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL31441688 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL17848342 | 0.81 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL22346052 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL31316605 | 0.79 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL3373334 | 0.78 | GAA (0.51) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 | |
| SCHEMBL288509 | 0.78 | GAA (0.51) | ALDH1A1LMNAMAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710458-A1 | IMMUNOPROTEASOME INHIBITORS | Principia Biopharma Inc. (US) | 2020-09-23 | — | — | EP | disclosed |