Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17848342 | 0.92 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17848607 | 0.90 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17848404 | 0.89 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL22346857 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGAACYP1A2 | |
| SCHEMBL24362694 | 0.84 | RORC (0.50) | ALDH1A1LMNAMAPT | |
| SCHEMBL31316578 | 0.84 | NR1H2 (0.46) | ALDH1A1LMNAMAPT | |
| SCHEMBL31316657 | 0.83 | RORC (0.46) | ALDH1A1LMNAMAPTATM | |
| SCHEMBL17848690 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17848569 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTPOLBCYP1A2 | |
| SCHEMBL31441492 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025010311-A1 | UREA-CONTAINING AGONISTS OF OREXIN RECEPTOR TYPE 2 | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-01-09 | — | — | WO | disclosed |