SCHEMBL2244010

SCHEMBL2244010

Cc1cccc(O)c1C(C(C)(C)C)C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.52
ATM Q13315 2/20 0.52
ALDH1A1 P00352 3/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
CA2 P00918 3/20 0.36
CA1 P00915 2/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 1/20 0.35
GAA P10253 3/20 0.33
ESR1 P03372 3/20 0.33
DAO P14920 2/20 0.33
DDO Q99489 2/20 0.33
MGAM O43451 2/20 0.33
SI P14410 2/20 0.33
MGAM2 Q2M2H8 2/20 0.33
CYP1A2 P05177 2/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184407 0.76 TRPA1 (0.52) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL30309279 0.76 TRPA1 (0.52) TRPA1ATMALDH1A1GABRA1GABRB2
Water SCHEMBL27928522 0.74 TRPA1 (0.50) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL6656127 0.74 TRPA1 (0.50) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL29558466 0.74 TRPA1 (0.50) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL9197954 0.72 TRPA1 (0.48) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL24824296 0.71 TRPA1 (0.41) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL9169241 0.71 TRPA1 (0.46) TRPA1ATMALDH1A1CA2CA1
SCHEMBL11065629 0.69 TRPA1 (0.45) TRPA1ATMALDH1A1GABRA1GABRB2
SCHEMBL8496181 0.69 TRPA1 (0.45) TRPA1ATMALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110190464-A1 METHOD FOR THE SYNTHESIS OF BIORESOURCED ACRYLIC ACID ESTERS ARKEMA FRANCE (FR) 2011-08-04 US disclosed