SCHEMBL11065629

SCHEMBL11065629

C=CC(C)c1c(C)cccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 4/20 0.39
CA1 P00915 6/20 0.37
CA2 P00918 6/20 0.37
CA9 Q16790 5/20 0.37
CA7 P43166 4/20 0.37
CA12 O43570 3/20 0.37
CA14 Q9ULX7 3/20 0.37
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
THRB P10828 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
RECQL P46063 2/20 0.34
POLB P06746 1/20 0.34
MPI P34949 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184407 0.79 TRPA1 (0.52) TRPA1ATMALDH1A1CA1CA2
SCHEMBL30309279 0.79 TRPA1 (0.52) TRPA1ATMALDH1A1CA1CA2
SCHEMBL29558466 0.77 TRPA1 (0.50) TRPA1ATMALDH1A1CA1CA2
Water SCHEMBL27928522 0.77 TRPA1 (0.50) TRPA1ATMALDH1A1CA1CA2
SCHEMBL28827495 0.77 PPARG (0.40) TRPA1ATMALDH1A1KDM4EMAPT
SCHEMBL9197954 0.75 TRPA1 (0.48) TRPA1ATMALDH1A1CA1CA2
SCHEMBL9908787 0.74 ALDH1A1 (0.48) TRPA1ATMALDH1A1CA1CA2
SCHEMBL7937960 0.73 LMNA (0.53) ATMALDH1A1CA1CA2CA9
SCHEMBL24804430 0.72 ALDH1A1 (0.39) TRPA1ATMALDH1A1CA1CA2
SCHEMBL6656127 0.72 TRPA1 (0.50) TRPA1ATMALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4428868-A 5-Methyl-2-(2'-oxo-3'-butyl)phenol and perfume compositions comprising same TAKASAGO PERFUMERY CO., LTD. (JP) 1984-01-31 US disclosed
EP-0058906-B1 5-METHYL-2-(2'-OXO-3'-BUTYL) PHENOL AND PERFUME COMPOSITIONS COMPRISING SAME Takasago Perfumery Co., Ltd. (JP) 1984-01-25 EP disclosed
EP-0058906-A1 5-Methyl-2-(2'-oxo-3'-butyl) phenol and perfume compositions comprising same Takasago Perfumery Co., Ltd. (JP) 1982-09-01 EP disclosed