Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 2/20 | 0.61 |
| ▸ | FURIN | P09958 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MTOR | P42345 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635795 | 1.00 | OGG1 (0.61) | OGG1FURINCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1562150 | 0.88 | KDM4E (0.67) | OGG1CYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL6636895 | 0.88 | KDM4E (0.67) | OGG1CYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL1562152 | 0.88 | KDM4E (0.67) | OGG1CYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL6636836 | 0.87 | OGG1 (0.70) | OGG1FURINCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6634931 | 0.83 | MAPT (0.61) | OGG1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29586571 | 0.83 | MAPT (0.61) | OGG1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1563270 | 0.83 | MAPT (0.61) | OGG1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1563268 | 0.83 | MAPT (0.61) | OGG1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6635616 | 0.82 | RAB9A (0.55) | OGG1FURINCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725838-A1 | RUBBER COMPOSITION FOR TIRE TREAD AND TIRE | Bridgestone Corporation (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-20200299490-A1 | RUBBER COMPOSITION FOR TIRE TREAD AND TIRE | BRIDGESTONE CORPORATION (JP) | 2020-09-24 | — | — | US | disclosed |