SCHEMBL22442012

SCHEMBL22442012

Oc1ccc(C=Cc2cc(O)c(Cl)c(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.64
ACE P12821 1/20 0.64
NQO2 P16083 3/20 0.63
LCK P06239 2/20 0.63
KDM4E B2RXH2 4/20 0.61
MEN1 O00255 4/20 0.61
MAPT P10636 4/20 0.61
KMT2A Q03164 4/20 0.61
APP P05067 4/20 0.61
TTR P02766 4/20 0.61
ALOX5 P09917 4/20 0.61
MAOB P27338 3/20 0.61
ALDH1A1 P00352 3/20 0.61
LMNA P02545 3/20 0.61
TP53 P04637 3/20 0.61
CYP1A2 P05177 3/20 0.61
CYP3A4 P08684 3/20 0.61
CYP2C9 P11712 3/20 0.61
HPGD P15428 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23883121 0.84 PTPN1 (0.68) PTGS1ACENQO2LCKKDM4E
SCHEMBL5960453 0.83 AHR (0.58) PTGS1ACELCKKDM4EMEN1
SCHEMBL5960449 0.83 AHR (0.58) PTGS1ACELCKKDM4EMEN1
SCHEMBL718527 0.82 PTGS1 (0.69) PTGS1ACENQO2LCKKDM4E
SCHEMBL718526 0.82 PTGS1 (0.69) PTGS1ACENQO2LCKKDM4E
SCHEMBL18329574 0.78 PTGS1 (0.64) PTGS1ACENQO2LCKKDM4E
SCHEMBL29057863 0.78 PTGS1 (0.64) PTGS1ACENQO2LCKKDM4E
SCHEMBL30285827 0.78 PTGS1 (1.00) PTGS1ACENQO2LCKKDM4E
SCHEMBL6266989 0.78 APP (0.74) PTGS1ACENQO2LCKKDM4E
Trans-4,4'-Dihydroxystilbene SCHEMBL491346 0.78 APP (0.74) PTGS1ACENQO2LCKKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200299671-A1 IMMOBILIZED MULTI-ENZYMATIC HALOGENATION SYSTEM UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2020-09-24 US disclosed