Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960449 | 1.00 | AHR (0.58) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL22442012 | 0.83 | PTGS1 (0.64) | PTGS1TTRALOX5PTGS2TRPA1 | |
| 3,4,5-Trihydroxy-Transstilbene SCHEMBL41160 | 0.82 | PTGS2 (0.63) | AHRPTGS1TTRALOX5PTGS2 | |
| 3,4,5-Trihydroxy-Transstilbene SCHEMBL41159 | 0.82 | PTGS2 (0.63) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL27388811 | 0.79 | TUBB1 (0.56) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL919450 | 0.78 | AHR (0.58) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL5960441 | 0.78 | PTGS1 (0.64) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL919452 | 0.78 | AHR (0.58) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL5960445 | 0.78 | PTGS1 (0.64) | AHRPTGS1TTRALOX5PTGS2 | |
| SCHEMBL27882848 | 0.78 | AHR (0.58) | AHRPTGS1TTRALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | disclosed |