SCHEMBL22443294

SCHEMBL22443294

O=C(O)c1c(Br)n(-c2ccccc2)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GAA P10253 1/20 0.47
GFER P55789 1/20 0.47
FOLH1 Q04609 1/20 0.47
AGTR1 P30556 4/20 0.46
KMT2A Q03164 1/20 0.46
EGFR P00533 1/20 0.45
ALDH1A1 P00352 3/20 0.45
REN P00797 4/20 0.44
RORC P51449 1/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42
RECQL P46063 1/20 0.42
PLA2G2A P14555 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1076360 0.91 GAA (0.49) KDM4EATML3MBTL1GAAGFER
SCHEMBL28263719 0.84 KDM4E (0.46) KDM4EATML3MBTL1GAAGFER
SCHEMBL15175928 0.79 GAA (0.70) KDM4EATML3MBTL1GAAGFER
SCHEMBL10563973 0.79 KDM4E (0.52) KDM4EATML3MBTL1GAAGFER
SCHEMBL1144414 0.79 KDM4E (0.52) KDM4EATML3MBTL1GAAGFER
SCHEMBL12091703 0.78 AGTR1 (0.65) KDM4EATML3MBTL1GAAGFER
Hydrochloric Acid SCHEMBL11558081 0.78 KDM4E (0.50) KDM4EATML3MBTL1GAAGFER
SCHEMBL1144367 0.78 REN (0.65) KDM4EATML3MBTL1RENPOLB
SCHEMBL8998965 0.77 EGFR (0.63) KDM4EATML3MBTL1AGTR1EGFR
SCHEMBL30385665 0.76 EGFR (0.42) KDM4EATML3MBTL1GAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3941920-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-03-20 EP disclosed
US-20220177478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK KGAA (DE) 2022-06-09 US disclosed
EP-3941920-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2022-01-26 EP disclosed
WO-2020187865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-24 WO disclosed
WO-2020187865-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220177478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM KDM4E 1889/4885ATM 3068/4885L3MBTL1 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.