SCHEMBL22444449

SCHEMBL22444449

CCOCCCCCCCN=C=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.34
CES2 O00748 1/20 0.31
ALDH1A1 P00352 2/20 0.31
EPHX2 P34913 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23797171 1.00 NAAA (0.34) NAAACES2ALDH1A1EPHX2TSHR
SCHEMBL22444838 1.00 NAAA (0.34) NAAACES2ALDH1A1EPHX2TSHR
SCHEMBL1492992 1.00 NAAA (0.34) NAAACES2ALDH1A1EPHX2TSHR
SCHEMBL15121286 1.00 NAAA (0.34) NAAACES2ALDH1A1EPHX2TSHR
SCHEMBL22444470 1.00 NAAA (0.34) NAAACES2ALDH1A1EPHX2TSHR
SCHEMBL15121232 0.98 ALDH1A1 (0.32) NAAAALDH1A1TSHR
SCHEMBL6581210 0.91
SCHEMBL23797152 0.87 NAAA (0.30) NAAA
SCHEMBL23797155 0.87 NAAA (0.30) NAAA
SCHEMBL16949970 0.87 NAAA (0.30) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230086342-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2023-03-23 US disclosed
EP-4118161-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES Covestro Deutschland AG (DE) 2023-01-18 EP disclosed
CN-113574041-A Method for producing bisphenol and method for producing polycarbonate resin 三菱化学株式会社 2021-10-29 CN disclosed
WO-2021180709-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2021-09-16 WO disclosed
EP-3878914-A1 USE OF SPECIFIC OPEN-CHAIN ETHER ISOCYANATES Covestro Deutschland AG (DE) 2021-09-15 EP disclosed
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed