SCHEMBL22444555

SCHEMBL22444555

CCCCC(O)(N=C=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.40
SIGMAR1 Q99720 1/20 0.36
CHRM2 P08172 2/20 0.36
CHRM3 P20309 2/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
ESR2 Q92731 4/20 0.35
ESR1 P03372 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22444521 0.95 GAA (0.41) KIF11SIGMAR1CHRM2CHRM3GAA
SCHEMBL22444455 0.94 GAA (0.40) SIGMAR1CHRM2CHRM3GAAKMT2A
SCHEMBL22444534 0.94 GAA (0.40) SIGMAR1CHRM2CHRM3GAAKMT2A
SCHEMBL22444764 0.94 GAA (0.40) SIGMAR1CHRM2CHRM3GAAKMT2A
SCHEMBL22444735 0.90 CYP2C19 (0.37) KIF11SIGMAR1GAAL3MBTL1LMNA
SCHEMBL16944028 0.78 SIGMAR1 (0.31) SIGMAR1LMNA
SCHEMBL9132729 0.77 EBP (0.39) KIF11SIGMAR1GAAKMT2ATDP1
SCHEMBL5892151 0.76 KCNN4 (0.34) KIF11SIGMAR1GAAL3MBTL1LMNA
SCHEMBL6902889 0.73 CYP1A2 (0.37) HTTKMT2AALDH1A1MAPT
SCHEMBL17942152 0.72 KCNN4 (0.36) KIF11CHRM2CHRM3GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020189201-A1 METHOD FOR PRODUCING BISPHENOL AND METHOD FOR PRODUCING POLYCARBONATE RESIN 三菱ケミカル株式会社 2020-09-24 WO disclosed