SCHEMBL22445

SCHEMBL22445

[CH2]CCCCCC1CCCC1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.56
CYP1A2 P05177 1/20 0.48
KDM5A P29375 3/20 0.38
PHF8 Q9UPP1 3/20 0.38
KDM2A Q9Y2K7 3/20 0.38
KDM4C Q9H3R0 2/20 0.38
KDM4A O75164 1/20 0.37
EPHX1 P07099 1/20 0.35
NAAA Q02083 2/20 0.34
GPR84 Q9NQS5 1/20 0.34
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1867938 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL15971435 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL3026718 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL5707624 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL10385540 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL2407510 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL8405052 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL2877973 1.00 SIGMAR1 (0.56) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL8499356 0.97 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A
SCHEMBL65834 0.97 SIGMAR1 (0.60) SIGMAR1CYP1A2KDM5APHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 541 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259752-A2 Saccharide phosphates, their esters and method for their preparation BAYER AG (DE) 1988-03-16 EP claimed
US-20240239922-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-07-18 US disclosed
CN-118339233-A Compositions comprising polyarylene (ether) sulfones 巴斯夫欧洲公司 2024-07-12 CN disclosed
CN-118290219-A Synthesis method of alkyl indene compound 中山大学 2024-07-05 CN disclosed
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
US-20240191003-A1 COMPOSITION AND PHOTOSENSITIVE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-06-13 US disclosed
US-11981794-B2 Curable composition, cured product, and compound TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-14 US disclosed
US-20240141085-A1 PHOTOCURABLE LIQUID COMPOSITION, CURED PRODUCT, AND METHOD FOR PRODUCING CURED PRODUCT TOKYO OHKA KOGYO CO., LTD. (JP) 2024-05-02 US disclosed
US-11926681-B2 Curable composition, cured product, and method for producing cured product TOKYO OHKA KOGYO CO., LTD. (JP) 2024-03-12 US disclosed
EP-4317196-A1 PHOTOCURABLE COMPOSITION TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-07 EP disclosed
EP-0143385-A2 Phosphorylised glycosil amides, ureas, carbamates and thiocarbamates, method for their preparation and their use BAYER AG (DE) 1985-06-05 EP disclosed
EP-0137163-A2 3-Indolecarboxamide derivatives Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-04-17 EP disclosed
EP-0111448-A2 Colour-photographic recording material CIBA-GEIGY AG (CH) 1984-06-20 EP disclosed
US-4452884-A 2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL HYDROXYPHENYL ALKYL AMIDES OR ESTERS AS LIGHT STABILIZERS CIBA-GEIGY AG (CH) 1984-06-05 US disclosed
EP-0082817-A1 Colour-photographic recording material CIBA-GEIGY AG (CH) 1983-06-29 EP disclosed
US-4389345-A 3-Oxoestra-17-acetonitrile and unsaturated analogs G.D. SEARLE & CO. (US) 1983-06-21 US disclosed
EP-0077040-A1 3-Oxaestra-17-acetonitrile and unsaturated analogs, a process for their preparation and pharmaceutical compositions containing said compounds G.D. Searle & Co. (US) 1983-04-20 EP disclosed
US-4364950-A 5-Cyano-prostacyclin derivatives and use as medicines SCHERING AKTIENGESELLSCHAFT (DE) 1982-12-21 US disclosed
US-4198429-A BRONCHOSPASMOLYTIC HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
EP-0007319-A1 Indan-1-carboxylic acid derivatives,process for their preparation and pharmaceutical preparations containing these compounds SCHERING AKTIENGESELLSCHAFT (DE) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240192593-A1 PHOTOSENSITIVE COMPOSITION PPOX, ERCC1, ERCC5 SIGMAR1 4678/4885CYP1A2 3273/4885KDM5A 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.