Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445545 | 0.87 | NCF1 (0.53) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL29357479 | 0.87 | NCF1 (0.53) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL22441524 | 0.87 | NCF1 (0.53) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL22441526 | 0.87 | NCF1 (0.53) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL22441534 | 0.80 | EHMT2 (0.52) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL22445496 | 0.80 | EHMT2 (0.52) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL28688135 | 0.78 | EHMT2 (0.56) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL28688137 | 0.78 | EHMT2 (0.56) | NCF1EHMT2EHMT1PDGFRBPDGFRA | |
| SCHEMBL22441506 | 0.77 | NCF1 (0.54) | NCF1EHMT2EHMT1PDGFRBNPC1 | |
| SCHEMBL22441574 | 0.77 | EHMT2 (0.63) | NCF1EHMT2EHMT1PDGFRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190912-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |