Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.65 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.56 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 8/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358220 | 1.00 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445672 | 0.92 | NCF1 (0.57) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445652 | 0.91 | EHMT2 (0.59) | NCF1EHMT2EHMT1PDGFRBPDE3A | |
| SCHEMBL22445598 | 0.88 | NCF1 (0.51) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22441515 | 0.87 | NCF1 (0.59) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445487 | 0.87 | NCF1 (0.59) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22441445 | 0.87 | NCF1 (0.59) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22441558 | 0.87 | NCF1 (0.59) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445606 | 0.86 | NCF1 (0.70) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL30446792 | 0.85 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190912-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |