Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.59 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.59 |
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358220 | 0.91 | NCF1 (0.65) | EHMT2EHMT1NCF1FLT3PDGFRB | |
| SCHEMBL22445552 | 0.91 | NCF1 (0.65) | EHMT2EHMT1NCF1FLT3PDGFRB | |
| SCHEMBL22445672 | 0.91 | NCF1 (0.57) | EHMT2EHMT1NCF1FLT3PDGFRB | |
| SCHEMBL22441473 | 0.90 | EHMT2 (0.55) | EHMT2EHMT1NCF1FLT3PDPK1 | |
| SCHEMBL29354516 | 0.90 | EHMT2 (0.55) | EHMT2EHMT1NCF1FLT3PDPK1 | |
| SCHEMBL22445583 | 0.90 | EHMT2 (0.55) | EHMT2EHMT1NCF1FLT3PDPK1 | |
| SCHEMBL29354446 | 0.89 | EHMT2 (0.54) | EHMT2EHMT1NCF1FLT3PDPK1 | |
| SCHEMBL22441477 | 0.89 | EHMT2 (0.54) | EHMT2EHMT1NCF1FLT3PDPK1 | |
| SCHEMBL22445632 | 0.85 | EHMT2 (0.52) | EHMT2EHMT1NCF1FLT3PDGFRB | |
| SCHEMBL22455175 | 0.84 | EHMT2 (0.49) | EHMT2EHMT1NCF1FLT3PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190912-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |