Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813998 | 0.78 | IDO1 (0.40) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL2559434 | 0.77 | IDO1 (0.38) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL21495057 | 0.76 | IDO1 (0.37) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL166469 | 0.76 | IDO1 (0.37) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL9818286 | 0.74 | HTT (0.42) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL2513507 | 0.74 | GABRA1 (0.46) | CA2CA4CA5AALDH1A1CYP3A4 | |
| SCHEMBL7195097 | 0.74 | IDO1 (0.40) | IDO1TDO2CYP2C9ALDH1A1CYP3A4 | |
| SCHEMBL24017066 | 0.74 | IDO1 (0.47) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL3256312 | 0.74 | IDO1 (0.47) | IDO1TDO2CA1CA2CA4 | |
| SCHEMBL3675827 | 0.74 | IDO1 (0.47) | IDO1TDO2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941905-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020191151-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | ONCOVALENT THERAPEUTICS INC. (US) | 2020-09-24 | — | — | WO | disclosed |