Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.68 |
| ▸ | EHMT2 | Q96KQ7 | 5/20 | 0.58 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688127 | 0.90 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445491 | 0.88 | NCF1 (0.62) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22441475 | 0.88 | NCF1 (0.62) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| Hydrochloric Acid SCHEMBL22441512 | 0.87 | NCF1 (0.61) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22455395 | 0.85 | EHMT2 (0.59) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22455216 | 0.84 | NCF1 (0.71) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL31457629 | 0.83 | NCF1 (0.75) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445552 | 0.82 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL29358220 | 0.82 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL28931424 | 0.81 | NCF1 (0.55) | NCF1EHMT2EHMT1NPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190912-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |