Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19280067 | 0.85 | SMN1; SMN2 (0.35) | SMN1; SMN2CRBN | |
| SCHEMBL22445794 | 0.79 | — | — | |
| SCHEMBL21245148 | 0.74 | GAA (0.33) | — | |
| SCHEMBL19919573 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2CRBN | |
| SCHEMBL20869163 | 0.71 | FFAR3 (0.30) | — | |
| SCHEMBL27488808 | 0.68 | SMN1; SMN2 (0.34) | SMN1; SMN2CRBN | |
| SCHEMBL26136524 | 0.67 | NR1H2 (0.38) | SMN1; SMN2CRBN | |
| SCHEMBL19919507 | 0.67 | TOP2A (0.38) | SMN1; SMN2CRBN | |
| SCHEMBL17535563 | 0.64 | APLNR (0.31) | — | |
| SCHEMBL5328437 | 0.64 | SMN1; SMN2 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191261-A1 | INDAZOLES AS LRRK2 INHIBITORS | E-SCAPE BIO, INC. (US) | 2020-09-24 | — | — | WO | disclosed |