SCHEMBL224469

SCHEMBL224469

O=C(O)c1cc(Cl)ccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
TP53 P04637 2/20 1.00
TSHR P16473 2/20 0.68
CASP1 P29466 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
KDM4E B2RXH2 2/20 0.58
ERCC5 P28715 1/20 0.58
FEN1 P39748 1/20 0.58
HSD17B10 Q99714 1/20 0.58
TDP1 Q9NUW8 2/20 0.57
RAB9A P51151 2/20 0.57
NPC1 O15118 1/20 0.57
POLB P06746 1/20 0.57
MAPT P10636 1/20 0.57
MRGPRX4 Q96LA9 1/20 0.56
LMNA P02545 2/20 0.55
AKR1C4 P17516 1/20 0.54
AKR1C3 P42330 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL29282730 0.98 ALDH1A1 (0.95) ALDH1A1TP53TSHRCASP1SMN1; SMN2
SCHEMBL6584266 0.98 ALDH1A1 (0.95) ALDH1A1TP53TSHRCASP1SMN1; SMN2
Hydrochloric Acid SCHEMBL699002 0.98 ALDH1A1 (0.95) ALDH1A1TP53TSHRCASP1SMN1; SMN2
Naphthalene SCHEMBL28157459 0.90 ALDH1A1 (0.81) ALDH1A1TP53TSHRCASP1SMN1; SMN2
Tetrahydrofuran SCHEMBL28253593 0.85 ALDH1A1 (0.72) ALDH1A1TP53TSHRCASP1SMN1; SMN2
SCHEMBL1000440 0.83 ALDH1A1 (0.71) ALDH1A1TP53TSHRCASP1SMN1; SMN2
SCHEMBL19514758 0.83 ALDH1A1 (0.71) ALDH1A1TP53TSHRCASP1SMN1; SMN2
SCHEMBL8160214 0.83 ALDH1A1 (0.71) ALDH1A1TP53TSHRCASP1SMN1; SMN2
SCHEMBL13401358 0.82 ALDH1A1 (0.69) ALDH1A1TP53TSHRCASP1SMN1; SMN2
Triethylene Glycol SCHEMBL6939085 0.82 ALDH1A1 (0.68) ALDH1A1TP53TSHRCASP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119978403-A Coordination polymer based on pesticide ligand, preparation method and application thereof 北京农学院 2025-05-13 CN claimed
CN-119153167-B Strong-radiation-resistant nuclear power station reactor roof cable and preparation method thereof 江苏赛德电气有限公司 2025-04-18 CN claimed
CN-119715841-A Detection method for separating and measuring related substances in 2, 5-dichlorobenzoic acid 深圳万乐药业有限公司 2025-03-28 CN claimed
CN-118790960-B Hollow nano tubular carbon nitride structure modification and photocatalytic decomposition hydrogen production method 中国电建集团西北勘测设计研究院有限公司 2025-01-14 CN claimed
CN-119153167-A Strong-radiation-resistant nuclear power station reactor roof cable and preparation method thereof 江苏赛德电气有限公司 2024-12-17 CN claimed
CN-116462968-B Preparation and application of modified graphene oxide/polyvinylidene fluoride/carboxymethyl polyphenyl thioether composite material 西北师范大学 2024-10-22 CN claimed
CN-118790960-A Hollow nano tubular carbon nitride structure modification and photocatalytic decomposition hydrogen production method 中国电建集团西北勘测设计研究院有限公司 2024-10-18 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118206427-A Preparation method of 2,2', 5' -tetrachlorobiphenyl 上海泰坦科技股份有限公司 2024-06-18 CN claimed
EP-0902683-A1 AGONISTS IN THE COSTIMULATION OF TcR/CD3-INDUCED T-LYMPHOCYTES RADOPATH LIMITED (GB) 1999-03-24 EP claimed
WO-1998051685-A1 METHOD OF MANUFACTURING SERTINDOLE H. LUNDBECK A/S (DK) 1998-11-19 WO claimed
WO-1997034593-A1 AGONISTS IN THE COSTIMULATION OF TcR/CD3-INDUCED T-LYMPHOCYTES RADOPATH LIMITED (GB) 1997-09-25 WO claimed
EP-0751768-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1997-01-08 EP claimed
CN-1124012-A Arylating medicaments RADOPATH LTD (GB) 1996-06-05 CN claimed
EP-0539274-B1 Method for the synthesis of aldehydes and of their derivatives RHONE POULENC CHIMIE (FR) 1996-04-10 EP claimed
EP-0700287-A1 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1996-03-13 EP claimed
EP-0677292-A1 Anti-viral and anti-cancer agents RADOPATH LIMITED (GB) 1995-10-18 EP claimed
WO-1995024897-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1995-09-21 WO claimed
WO-1994027584-A2 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1994-12-08 WO claimed