Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11842389 | 0.89 | RECQL (0.77) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL11851362 | 0.88 | ALDH1A1 (0.57) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL3253860 | 0.88 | RECQL (0.80) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL7466437 | 0.87 | ALDH1A1 (0.61) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL13401358 | 0.84 | ALDH1A1 (0.69) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL29612638 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL230930 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL11851691 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TP53RECQLERCC5FEN1 | |
| SCHEMBL6940121 | 0.83 | RECQL (0.58) | ALDH1A1TP53RECQLSMN1; SMN2LMNA | |
| SCHEMBL611188 | 0.83 | RECQL (0.58) | ALDH1A1TP53RECQLSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007501-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| WO-1999010310-A1 | PROCESS FOR PRODUCING DIPHENYLETHERS AND ESTERS | THE DOW CHEMICAL COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| CN-105814059-B | Imidazo pyrimidine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-105814061-B | Imidazopyridazine derivative as TNF active regulators | UCB生物制药私人有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |
| CN-104470924-A | Imidazopyrazine derivatives as modulators of tnf activity | UCB PHARMA SA | 2015-03-25 | — | — | CN | disclosed |
| CN-1946754-B | Branched polyphenylene polymers | SOLVAY ADVANCED POLYMERS LLC | 2010-05-26 | — | — | CN | disclosed |
| CN-101072809-A | Preparation of substituted polyphenylenes by supported transition metal catalysis | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2007-11-14 | — | — | CN | disclosed |
| CN-1320021-C | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS (DE) | 2007-06-06 | — | — | CN | disclosed |
| CN-1946754-A | Branched polyphenylene polymers | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2007-04-11 | — | — | CN | disclosed |
| CN-1743355-A | Sulfonic group-containing polyarylene block copolymer, process for production thereof, solid polymer electrolyte and proton conductive membrane | JSR CORP (JP) | 2006-03-08 | — | — | CN | disclosed |
| CN-1705696-A | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS (DE) | 2005-12-07 | — | — | CN | disclosed |
| US-5110940-A | Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase | BRISTOL-MYERS COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5068346-A | Anticholesterol agents | BRISTOL-MYERS COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| US-4897490-A | DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE | BRISTOL-MEYERS COMPANY (US) | 1990-01-30 | — | — | US | disclosed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |
| US-3956324-A | THERMOPLASTIC POLYMER | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |