SCHEMBL2244750

SCHEMBL2244750

CC(C)(C)c1ccccc1C(=O)OOC(=O)c1ccccc1C(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
TSHR P16473 5/20 0.45
TDP1 Q9NUW8 3/20 0.45
MAPT P10636 2/20 0.42
POLB P06746 1/20 0.42
LMNA P02545 2/20 0.41
CA2 P00918 2/20 0.41
F2 P00734 1/20 0.41
HSD17B10 Q99714 2/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.39
ELANE P08246 1/20 0.39
CFTR P13569 1/20 0.38
KDM4E B2RXH2 2/20 0.38
GAA P10253 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
CA1 P00915 1/20 0.38
CA5A P35218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23529359 0.91 LMNA (0.59) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL4605817 0.90 ALDH1A1 (0.41) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL27909331 0.90 MAPT (0.43) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL28065042 0.89 ALDH1A1 (0.39) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL220622 0.89 ALDH1A1 (0.58) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL28043857 0.89 ALDH1A1 (0.39) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL28808753 0.89 MAPT (0.41) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL28206430 0.87 ALDH1A1 (0.43) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL5163249 0.87 CA12 (0.44) ALDH1A1TSHRTDP1MAPTPOLB
SCHEMBL14976 0.86 MAPT (0.44) ALDH1A1TSHRTDP1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330880-A Method for preparing quinolinone series compounds by dehydrogenating dihydroquinolinone series compounds 河南中医药大学 2025-01-21 CN claimed
CN-118852996-A Preparation method of ultraviolet light curing polyvinylidene fluoride adhesive 浙江衢州巨塑化工有限公司 2024-10-29 CN claimed
CN-118834603-A Ultraviolet light curing polyvinylidene fluoride adhesive 浙江衢州巨塑化工有限公司 2024-10-25 CN claimed
CN-118440309-A Polyester chain extension method, polyester prepared by same and application thereof 华东理工大学 2024-08-06 CN claimed
CN-117551273-B Functional auxiliary agent for underfill, preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-04-05 CN claimed
CN-117700604-A Single-component acrylic resin resistant to 84 disinfectant soaking and preparation method thereof 江苏三木化工股份有限公司 2024-03-15 CN claimed
CN-117700608-A Hydrophobic weather-resistant acrylic resin and preparation method thereof 江苏三木化工股份有限公司 2024-03-15 CN claimed
CN-115073651-B Water-based acrylic resin for glass bottle and preparation method thereof 江苏三木化工股份有限公司 2024-01-30 CN claimed
CN-115073651-A Water-based acrylic resin for glass bottles and preparation method thereof 江苏三木化工股份有限公司 2022-09-20 CN claimed
CN-109705259-B Scratch-resistant high-surface-hardness thermoplastic resin, plastic and preparation method 金旸(厦门)新材料科技有限公司 2020-12-11 CN claimed
CN-111793160-A Water-based acrylic resin for industrial baking varnish and preparation method thereof 江苏三木化工股份有限公司 2020-10-20 CN claimed
CN-106496130-B A kind of methyl ketone derivatives and the preparation method and application thereof 苏州大学 2019-09-20 CN claimed
CN-105503635-B A kind of preparation method of the Dicarbonyl derivatives of 2 amido formacyl 1,3 苏州大学 2017-10-10 CN claimed
US-9464191-B2 Silicon-containing curing composition and cured product thereof ADEKA CORPORATION (JP) 2016-10-11 US claimed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
US-12578664-B2 Toner and method for producing toner CANON KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
US-4139697-A AZO OR PEROXY COMPOUNDS TENNECO CHEMICALS, INC. (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12578664-B2 Toner and method for producing toner C1R, TECR, FCGR2A ALDH1A1 4329/4885TSHR 224/4885TDP1 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.