Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 4/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | S100A9 | P06702 | 1/20 | 0.47 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.46 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.46 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551868 | 0.88 | PIK3CA (0.55) | PIK3CAMTORALDH1A1PIK3CGLMNA | |
| SCHEMBL15556197 | 0.87 | MTOR (0.55) | PIK3CAMTORALDH1A1PIK3CGPIK3CD | |
| SCHEMBL15648432 | 0.87 | PIK3CG (0.49) | CCR4PIK3CAMTORPIK3CGS100A9 | |
| SCHEMBL358926 | 0.87 | PIK3CG (0.63) | CCR4PIK3CAMTORPIK3CGS100A9 | |
| SCHEMBL29969873 | 0.86 | CCR4 (0.64) | CCR4PIK3CGMAP3K20PIK3CD | |
| SCHEMBL21513796 | 0.86 | CCR4 (0.64) | CCR4PIK3CGMAP3K20PIK3CD | |
| SCHEMBL28549695 | 0.86 | PIK3CG (0.50) | CCR4PIK3CAMTORPIK3CGS100A9 | |
| SCHEMBL22447721 | 0.85 | GLO1 (0.46) | CCR4PIK3CAMTORALDH1A1PIK3CG | |
| Ammonia Solution, Strong SCHEMBL28564473 | 0.85 | PIK3CG (0.49) | CCR4PIK3CAMTORPIK3CGS100A9 | |
| SCHEMBL789641 | 0.84 | MEN1 (0.52) | PIK3CAALDH1A1PIK3CGLMNAS100A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712143-A1 | QUINAZOLINONE COMPOUND AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |