⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691843 | 0.84 | — | — | |
| SCHEMBL7940571 | 0.83 | — | — | |
| SCHEMBL157507 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL7600945 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL7600940 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL6691821 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL6692444 | 0.75 | — | — | |
| Methoxymethane SCHEMBL28433374 | 0.74 | — | — | |
| SCHEMBL184319 | 0.74 | — | — | |
| SCHEMBL12855787 | 0.74 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46357-E1 | Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens | HOYA CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| EP-2040099-B1 | PHOTOCHROMIC FILM, PHOTOCHROMIC LENS COMPRISING THE SAME, AND METHOD OF MANUFACTURING PHOTOCHROMIC LENS | HOYA CORP (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-7999989-B2 | Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens | HOYA CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090316246-A1 | PHOTOCHROMIC FILM, PHOTOCHROMIC LENS COMPRISING THE SAME, AND METHOD OF MANUFACTURING PHOTOCHROMIC LENS | HOYA CORPORATION (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2040099-A1 | PHOTOCHROMIC FILM, PHOTOCHROMIC LENS HAVING THE SAME, AND PROCESS FOR PRODUCING PHOTOCHROMIC LENS | Hoya Corporation (JP) | 2009-03-25 | — | — | EP | disclosed |