Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019726 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL15037157 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL15037412 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL15019727 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL15037071 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL15037077 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL22449330 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL16380220 | 0.94 | ITGB3 (0.43) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL16305365 | 0.94 | ITGB1 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC | |
| SCHEMBL22756192 | 0.94 | ITGB1 (0.44) | ITGB3ITGA2BITGB1ITGA4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |