Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037077 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4S1PR1 | |
| SCHEMBL15037071 | 1.00 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4S1PR1 | |
| SCHEMBL16306079 | 0.97 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4S1PR1 | |
| SCHEMBL15037412 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL22449264 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL15019726 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL15037157 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL15019727 | 0.95 | ITGB3 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL22756192 | 0.95 | ITGB1 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 | |
| SCHEMBL16305365 | 0.95 | ITGB1 (0.44) | ITGB3ITGA2BITGB1ITGA4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |