Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093737 | 1.00 | CTSL (0.46) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL9425975 | 0.83 | CTSL (0.44) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL8640188 | 0.80 | CTSL (0.57) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL11814690 | 0.80 | CTSL (0.57) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL2700673 | 0.80 | CTSL (0.57) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL22449348 | 0.80 | CTSL (0.57) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL18669503 | 0.78 | CTSL (0.44) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL18678556 | 0.78 | CTSL (0.44) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL4569160 | 0.78 | CTSL (0.44) | CTSLCTSBCTSKEPHX2JAK2 | |
| SCHEMBL15359269 | 0.77 | CTSL (0.43) | CTSLCTSBCTSKEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288950-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-09-23 | — | — | EP | disclosed |