Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346290 | 0.89 | CTSL (0.52) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL18855865 | 0.86 | CTSL (0.48) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL11814690 | 0.84 | CTSL (0.57) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL22449348 | 0.84 | CTSL (0.57) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL2700673 | 0.84 | CTSL (0.57) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL8640188 | 0.84 | CTSL (0.57) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL20093737 | 0.83 | CTSL (0.46) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL22449352 | 0.83 | CTSL (0.46) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL18561604 | 0.80 | CTSL (0.46) | CTSLCTSBCTSKNPC1JAK2 | |
| SCHEMBL28832774 | 0.79 | CTSL (0.57) | CTSLCTSBCTSKNPC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286725-A | Pyridazinones endowed with acaricide and insecticide action | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-02-15 | — | — | US | disclosed |
| EP-0476573-A1 | 2-tButyl-4-chloro-5-(4-ibutylmethylcyclohexyl)-methylthio-3(H)-pyridazinone having acaricidal and insecticidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1992-03-25 | — | — | EP | disclosed |