Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 5/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067458 | 0.90 | CNR1 (0.47) | CNR1CNR2CREBBP | |
| SCHEMBL24067361 | 0.85 | CNR1 (0.42) | CNR1OPRK1 | |
| SCHEMBL22450676 | 0.84 | CNR1 (0.55) | CNR1CNR2CREBBP | |
| SCHEMBL24067461 | 0.83 | CNR1 (0.50) | CNR1CNR2HTR3A | |
| SCHEMBL24067323 | 0.82 | IL1B (0.41) | CNR1OPRK1CFD | |
| SCHEMBL22450925 | 0.81 | CNR1 (0.46) | CNR1CNR2HTR3ACREBBPCFD | |
| SCHEMBL22450851 | 0.81 | IL1B (0.49) | CNR1CNR2HTR3AOPRK1 | |
| SCHEMBL24067339 | 0.80 | CFD (0.41) | CNR1CFD | |
| SCHEMBL24067316 | 0.78 | IL1B (0.50) | CNR1 | |
| SCHEMBL24182198 | 0.78 | TNF (0.53) | CNR1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712162-A1 | SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |