Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451189 | 0.89 | APP (0.34) | ALDH1A1APPNPC1RAB9APOLB | |
| SCHEMBL26664061 | 0.86 | NPC1 (0.32) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL22451337 | 0.82 | APP (0.35) | APPNPC1RAB9APOLBPLK1 | |
| SCHEMBL22451177 | 0.82 | TSHR (0.34) | ALDH1A1APPNPC1RAB9APOLB | |
| SCHEMBL22451224 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL22451357 | 0.81 | APP (0.35) | ALDH1A1APPSMN1; SMN2PLK1CYSLTR2 | |
| SCHEMBL26664102 | 0.80 | APP (0.35) | ALDH1A1APPPLK1 | |
| SCHEMBL26663920 | 0.78 | NPC1 (0.32) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL22451253 | 0.78 | TDP1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL24345953 | 0.78 | NPC1 (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712138-A1 | BENZOTRIAZOLE COMPOUND | Miyoshi Oil & Fat Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |