Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22451254 | 0.90 | ALDH1A1 (0.33) | TDP1POLBALDH1A1NPC1KDM4E | |
| SCHEMBL22451359 | 0.88 | TDP1 (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26663595 | 0.85 | TDP1 (0.41) | TDP1POLBAPEX1HTTMAPK14 | |
| SCHEMBL22451353 | 0.81 | TSHR (0.37) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26665629 | 0.81 | MAPK14 (0.33) | TDP1POLBAPEX1HTTMAPK14 | |
| SCHEMBL22451203 | 0.80 | TSHR (0.34) | POLBTSHRALDH1A1NPC1KDM4E | |
| SCHEMBL22451322 | 0.80 | PTGS2 (0.34) | ALDH1A1 | |
| SCHEMBL22451256 | 0.79 | MAPT (0.41) | POLBMAPK14ALDH1A1NPC1KDM4E | |
| SCHEMBL22451365 | 0.78 | ALDH1A1 (0.35) | TDP1POLBALDH1A1NPC1KDM4E | |
| SCHEMBL22451255 | 0.78 | NPC1 (0.32) | TDP1POLBALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3712138-A1 | BENZOTRIAZOLE COMPOUND | Miyoshi Oil & Fat Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |