Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853505 | 0.81 | CA9 (0.44) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL26775387 | 0.81 | CA9 (0.44) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL8505406 | 0.78 | PBRM1 (0.46) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL29584703 | 0.78 | NTRK2 (0.56) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL4499446 | 0.78 | NTRK2 (0.56) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL618639 | 0.78 | CA12 (0.53) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL13264631 | 0.78 | MAOA (0.43) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL12240926 | 0.77 | PARP10 (0.51) | MAOAMAOBCA9CA1CA2 | |
| SCHEMBL26775546 | 0.76 | GRM5 (0.43) | ESR1MAOAMAOBESR2UGT1A1 | |
| SCHEMBL26775543 | 0.74 | CLK4 (0.46) | ESR1MAOAMAOBESR2UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299306-A1 | COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF | UNIVERSITA' DI PISA (IT) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299306-A1 | COMPOUNDS WITH A BENZO[A]CARBAZOLE STRUCTURE AND USE THEREOF | MKI67, CCNI, CASP3 | ESR1 1646/4885MAOA 708/4885MAOB 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.