Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4227930 | 0.74 | FBP1 (0.42) | MAPTALDH1A1CYP3A4G6PDLMNA | |
| SCHEMBL4227927 | 0.74 | FBP1 (0.42) | MAPTALDH1A1CYP3A4G6PDLMNA | |
| SCHEMBL4227933 | 0.74 | FBP1 (0.42) | MAPTALDH1A1CYP3A4G6PDLMNA | |
| SCHEMBL29096570 | 0.72 | ERN1 (0.49) | KDM4EGLAERN1MAPTALDH1A1 | |
| SCHEMBL29096568 | 0.72 | ERN1 (0.49) | KDM4EGLAERN1MAPTALDH1A1 | |
| SCHEMBL21812463 | 0.70 | KDM4E (0.42) | KDM4EGLAERN1MAPTALDH1A1 | |
| SCHEMBL27229848 | 0.68 | MAPT (0.35) | MAPTALDH1A1POLBLMNAKMT2A | |
| SCHEMBL27232550 | 0.68 | MAPT (0.35) | MAPTALDH1A1POLBLMNAKMT2A | |
| SCHEMBL791039 | 0.66 | ERN1 (0.57) | KDM4EGLAERN1PTGDR2MAPT | |
| SCHEMBL31456065 | 0.66 | PRKDC (0.41) | KDM4EERN1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190734-A1 | IMMUNOCONJUGATES TARGETING PD-L1 | BOLT BIOTHERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020190731-A1 | IMMUNOCONJUGATES TARGETING HER2 | BOLT BIOTHERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |
| WO-2020190760-A1 | IMMUNOCONJUGATES TARGETING CEA | BOLT BIOTHERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |