Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4227933 | 1.00 | FBP1 (0.42) | FBP1G6PDMAPTMEN1LMNA | |
| SCHEMBL4227930 | 1.00 | FBP1 (0.42) | FBP1G6PDMAPTMEN1LMNA | |
| SCHEMBL4631917 | 0.81 | FBP1 (0.56) | FBP1G6PDALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL4631916 | 0.81 | FBP1 (0.56) | FBP1G6PDALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL16030559 | 0.81 | FBP1 (0.56) | FBP1G6PDALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10401115 | 0.78 | FBP1 (0.50) | FBP1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL26976895 | 0.77 | FBP1 (0.47) | FBP1MAPTMEN1LMNAKMT2A | |
| SCHEMBL27793303 | 0.76 | FBP1 (0.70) | FBP1MAPTMEN1LMNAKMT2A | |
| SCHEMBL22451602 | 0.74 | CCR5 (0.37) | G6PDMAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL29248045 | 0.74 | FBP1 (0.49) | FBP1MAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026961-A1 | PROCESSES FOR THE PREPARATION OF PANCRATISTATIN AND PANCRATISTATIN ANALOGUES | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA (ES) | 2009-03-05 | — | — | WO | disclosed |