⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3018357 | 0.85 | — | — | |
| SCHEMBL774116 | 0.74 | LMNA (0.37) | — | |
| SCHEMBL14669290 | 0.74 | ESR2 (0.30) | — | |
| SCHEMBL17632024 | 0.74 | LMNA (0.37) | — | |
| SCHEMBL14205674 | 0.73 | — | — | |
| SCHEMBL23774154 | 0.72 | PHGDH (0.30) | — | |
| SCHEMBL9860061 | 0.72 | — | — | |
| SCHEMBL12949408 | 0.72 | EPHX1 (0.37) | — | |
| SCHEMBL14669355 | 0.72 | TRPA1 (0.30) | — | |
| SCHEMBL19054518 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190791-A1 | INHIBITING CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN (CREB) | FORMA THERAPEUTICS, INC. (US) | 2020-09-24 | — | — | WO | disclosed |