Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085509 | 0.88 | RPS6KA1 (0.47) | IDO1RPS6KA1CA1CA2CA12 | |
| SCHEMBL22452384 | 0.82 | PDCD1 (0.43) | PDCD1CD274IDO1MALT1TDP1 | |
| SCHEMBL22604986 | 0.81 | IDO1 (0.38) | PDCD1CD274IDO1MALT1TDP1 | |
| SCHEMBL18198091 | 0.81 | RIPK1 (0.50) | IDO1MALT1BCHENQO2MEN1 | |
| SCHEMBL26599167 | 0.79 | LMNA (0.44) | PDCD1CD274IDO1RPS6KA1MALT1 | |
| SCHEMBL26599039 | 0.79 | NQO2 (0.44) | PDCD1CD274IDO1RPS6KA1MALT1 | |
| SCHEMBL30606607 | 0.79 | LMNA (0.44) | PDCD1CD274IDO1RPS6KA1MALT1 | |
| SCHEMBL337290 | 0.78 | IDO1 (0.39) | PDCD1CD274IDO1MALT1TDP1 | |
| SCHEMBL29467981 | 0.78 | RPS6KA1 (0.42) | IDO1RPS6KA1TDP1NQO2CA1 | |
| SCHEMBL4708240 | 0.78 | IDO1 (0.50) | IDO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200340982-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION | 2020-10-29 | — | — | US | disclosed |
| WO-2020191339-A1 | PHOTOAFFINITY PROBES | PROMEGA CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |