Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10799825 | 0.91 | ESR1 (0.46) | ESR1S1PR1CYP1A2SMN1; SMN2MEN1 | |
| SCHEMBL9347243 | 0.85 | LTA4H (0.38) | ESR1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL242391 | 0.80 | KMT2A (0.46) | SMN1; SMN2MEN1KMT2ARAB9AMAPT | |
| SCHEMBL30848429 | 0.78 | KMT2A (0.45) | ESR1SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL5523437 | 0.78 | KMT2A (0.45) | SMN1; SMN2MEN1KMT2ARAB9AMAPT | |
| SCHEMBL10664734 | 0.78 | TSHR (0.47) | ESR1SMN1; SMN2KDM4ELTA4HTSHR | |
| SCHEMBL6302960 | 0.78 | ESR1 (0.48) | ESR1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL10660644 | 0.77 | RORC (0.42) | MEN1KMT2AKDM4ERAB9AMAPT | |
| SCHEMBL9324828 | 0.76 | CNR2 (0.49) | ESR1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL8521108 | 0.75 | CYP1A2 (0.42) | ESR1S1PR1CYP1A2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470242-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1230381-A4 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH INC (US) | 2004-10-13 | — | — | EP | claimed |
| US-6664073-B1 | Contacting with cystathionine beta-synthase, L-serine, and cystathionine beta-lyase to catalyze the cyclical conversion of homocysteine to cystathionine and the reconversion of cystathionine to homocysteine; pyruvate and NH3 | CATCH INC. | 2003-12-16 | — | — | US | claimed |
| US-6635438-B2 | Beta-synthase, L-serine, cystathionine beta-lyase; amount of pyruvate and/or ammonia produced from reconversion of cystathionine to homocysteine; improvement comprises completing the enzymatic conversion in less than 15 minutes | CATCH, INC. | 2003-10-21 | — | — | US | claimed |
| US-20030138872-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2003-07-24 | — | — | US | claimed |
| WO-2003040694-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| EP-1230381-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2002-08-14 | — | — | EP | claimed |
| WO-2001033187-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2001-05-10 | — | — | WO | claimed |
| EP-1470242-B1 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | AXIS SHIELD DIAGNOSTICS LTD (GB) | 2013-08-14 | — | — | EP | disclosed |
| EP-1230381-B1 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | AXIS SHIELD DIAGNOSTICS LTD (GB) | 2011-07-27 | — | — | EP | disclosed |
| US-6867014-B2 | Enzymatic cycling assays for homocysteine and cystathionine | CATCH, INC. | 2005-03-15 | — | — | US | disclosed |
| EP-1470242-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1230381-A4 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH INC (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040096929-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2004-05-20 | — | — | US | disclosed |
| US-6664073-B1 | Contacting with cystathionine beta-synthase, L-serine, and cystathionine beta-lyase to catalyze the cyclical conversion of homocysteine to cystathionine and the reconversion of cystathionine to homocysteine; pyruvate and NH3 | CATCH INC. | 2003-12-16 | — | — | US | disclosed |
| US-6635438-B2 | Beta-synthase, L-serine, cystathionine beta-lyase; amount of pyruvate and/or ammonia produced from reconversion of cystathionine to homocysteine; improvement comprises completing the enzymatic conversion in less than 15 minutes | CATCH, INC. | 2003-10-21 | — | — | US | disclosed |
| US-20030138872-A1 | Enzymatic cycling assays for homocysteine and cystathionine | AXIS-SHIELD DIAGNOSTICS, LTD. (GB) | 2003-07-24 | — | — | US | disclosed |
| WO-2003040694-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1230381-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | Catch, Inc. (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001033187-A2 | ENZYMATIC CYCLING ASSAYS FOR HOMOCYSTEINE AND CYSTATHIONINE | CATCH, INC. (US) | 2001-05-10 | — | — | WO | disclosed |