Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 12/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453402 | 0.92 | MAPT (0.51) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22452471 | 0.83 | MEN1 (0.63) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22452475 | 0.78 | MEN1 (0.58) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL9593627 | 0.78 | MEN1 (0.83) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22650202 | 0.77 | MEN1 (0.73) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL22453595 | 0.75 | KMT2A (0.51) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL9593591 | 0.74 | AKR1C3 (0.79) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL10834390 | 0.74 | MEN1 (0.77) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL10652538 | 0.74 | AKR1C3 (0.78) | MEN1LMNAKMT2APOLBMAPT | |
| SCHEMBL5676620 | 0.73 | MEN1 (0.75) | MEN1LMNAKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |