SCHEMBL224525

SCHEMBL224525

CCCC(C)(C)OC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.52
HSD17B10 Q99714 1/20 0.52
TSHR P16473 3/20 0.39
ALOX15 P16050 1/20 0.39
CYP3A4 P08684 1/20 0.39
NFKB1 P19838 1/20 0.39
ADRA1A P35348 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FDPS P14324 2/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ELANE P08246 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16244342 0.86 LMNA (0.44) LMNAHSD17B10TSHRALOX15CYP3A4
SCHEMBL27403746 0.85 LMNA (0.42) LMNAHSD17B10FDPSCA1CA2
SCHEMBL18719371 0.84 LMNA (0.40) LMNAHSD17B10TSHRCYP3A4NFKB1
SCHEMBL27992369 0.83 SMPD1 (0.42) LMNAHSD17B10FDPS
SCHEMBL29637097 0.83 SMPD1 (0.42) LMNAHSD17B10FDPS
SCHEMBL12274381 0.83 SMPD1 (0.42) LMNAHSD17B10FDPS
SCHEMBL28316089 0.83 SMPD1 (0.42) LMNAHSD17B10FDPS
Benzoic Acid SCHEMBL28723017 0.81 TSHR (0.44) LMNAHSD17B10TSHRCYP3A4TDP1
SCHEMBL30889164 0.81 LMNA (0.42) LMNAHSD17B10TSHRCYP3A4NFKB1
SCHEMBL18131107 0.81 LMNA (0.38) LMNAHSD17B10TSHRALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110585165-B Abuse resistant capsules R·P·谢勒技术有限公司 2022-08-12 CN claimed
CN-110585165-A Abuse resistant capsules R·P·谢勒技术有限公司 2019-12-20 CN claimed
CN-109689664-A The quinoline and azepine quinoline compound that tricyclic heteroaryl as PAR4 inhibitor replaces 百时美施贵宝公司 2019-04-26 CN claimed
CN-104936960-B Pyrrolo-pyrazole as N-type calcium channel blocker 詹森药业有限公司 2016-12-28 CN claimed
CN-105189464-A Cyclopentylpyrazoles as N-type calcium channel blockers JANSSEN PHARMACEUTICA NV 2015-12-23 CN claimed
CN-104936960-A Pyrrolopyrazoles as n-type calcium channel blockers JANSSEN PHARMACEUTICA NV 2015-09-23 CN claimed
CN-103974948-A Substituted benzyl indazoles as BUB1 kinase inhibitors in the treatment of hyperproliferative diseases Bayer Pharma AG 2014-08-06 CN claimed
CN-103347565-A Compositions and methods for treating ocular edema, neovascularization, and related diseases AKEBIA THERAPEUTICS INC 2013-10-09 CN claimed
CN-102365024-A Compounds, compositions and methods for preventing metastasis of cancer cells AKEBIA THERAPEUTICS INC 2012-02-29 CN claimed
CN-102216286-A Substituted (pyridyl)-azinylamine derivatives as plant protection agents BAYER CROPSCIENCE SA 2011-10-12 CN claimed
CN-101801975-A Pyrazolo-pyrazines derivatives used as g protein inhibitors IPSEN PHARMA SAS 2010-08-11 CN claimed
CN-101300239-A 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists ASTRAZENECA AB (SE) 2008-11-05 CN claimed
CN-101285061-A Fungal cell wall synthetic genes EISAI R&D MAN CO LTD (JP) 2008-10-15 CN claimed
CN-101243093-A New oxabispidine compounds for the treatment of cardiac arrhythmias ASTRAZENECA AB (SE) 2008-08-13 CN claimed
CN-1968957-A Novel oxabispidine compounds and their use in the treatment of cardiac arrhythmias ASTRAZENECA AB (SE) 2007-05-23 CN claimed
CN-1249227-C Fungal cell wall synthetic genes EISAI CO LTD (JP) 2006-04-05 CN claimed
CN-1688579-A Condensed pyridines and pyrimidines with TIE2 (TEK) activity ASTRAZENECA AB (SE) 2005-10-26 CN claimed
CN-1449443-A Fungal cell wall synthetic genes EISAI CO LTD (JP) 2003-10-15 CN claimed
WO-2024094637-A1 PROCESS FOR THE PREPARATION OF CYCLIC KETONES ARXADA AG (CH) 2024-05-10 WO disclosed
EP-0799823-A1 1,2-Diphenylpyrrole derivatives, their preparation and their therapeutic uses SANKYO COMPANY LIMITED (JP) 1997-10-08 EP disclosed