Sugi Predict

Sugi Predict / Compounds / SCHEMBL16244342

SCHEMBL16244342

SCHEMBL16244342

CCCCC(C)(C)OC(N)=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ FDPS P14324 3/20 0.38
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ ALOX15 P16050 1/20 0.36
▸ TSHR P16473 2/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ ADRA1A P35348 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CTSK P43235 2/20 0.33
▸ SMPD1 P17405 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ CES2 O00748 2/20 0.32
▸ CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27403746 0.94 LMNA (0.42) LMNAHSD17B10FDPSCA1CA2
SCHEMBL29637097 0.92 SMPD1 (0.42) LMNAHSD17B10FDPSSMPD1CES2
SCHEMBL28316089 0.92 SMPD1 (0.42) LMNAHSD17B10FDPSSMPD1CES2
SCHEMBL12274381 0.92 SMPD1 (0.42) LMNAHSD17B10FDPSSMPD1CES2
SCHEMBL27992369 0.92 SMPD1 (0.42) LMNAHSD17B10FDPSSMPD1CES2
SCHEMBL224525 0.86 LMNA (0.52) LMNAHSD17B10FDPSCA1CA2
SCHEMBL3077229 0.83 LMNA (0.35) LMNAHSD17B10FDPSALOX15TSHR
SCHEMBL27535729 0.83 CYP4F2 (0.40) LMNAHSD17B10ALOX15TDP1
SCHEMBL4346472 0.83 LMNA (0.44) LMNAHSD17B10FDPSCA1CA2
SCHEMBL8646937 0.82 CA1 (0.38) LMNAHSD17B10FDPSCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107001382-B Spiral shell-thiazolone 豪夫迈·罗氏有限公司 2019-10-25 — — CN claimed
WO-2024043261-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME 日本化薬株式会社 2024-02-29 — — WO disclosed
CN-114026199-B Polarized light emitting film, polarized light emitting panel and display device containing water-soluble coumarin compound or salt thereof 日本化药株式会社 2023-12-26 — — CN disclosed
US-11802208-B2 Stilbene-based compound or salt thereof, and polarizing film, polarizing plate, and display device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-10-31 — — US disclosed
CN-116348147-A Compositions for delivery of payload molecules to airway epithelium 摩登纳特斯有限公司 2023-06-27 — — CN disclosed
US-20230019461-A1 POLARIZED LIGHT-EMITTING FILM CONTAINING WATER-SOLUBLE COUMARIN COMPOUND OR SALT THEREOF, POLARIZED LIGHT-EMITTING PLATE, AND DISPLAY DEVICE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-01-19 — — US disclosed
CN-114829447-A Brush prodrug and use thereof 麻省理工学院 2022-07-29 — — CN disclosed
CN-110945083-B Styrene compound or salt thereof, polarizing film, polarizing plate and display device 日本化药株式会社 2022-07-01 — — CN disclosed
EP-3998502-A1 POLARIZED LIGHT-EMITTING FILM CONTAINING WATER-SOLUBLE COUMARIN COMPOUND OR SALT THEREOF, POLARIZED LIGHT-EMITTING PLATE, AND DISPLAY DEVICE Nippon Kayaku Kabushiki Kaisha (JP) 2022-05-18 — — EP disclosed
CN-114026199-A Polarizing luminescent film, polarizing luminescent sheet, and display device containing water-soluble coumarin compound or salt thereof 日本化药株式会社 2022-02-08 — — CN disclosed
CN-106967066-B Novel ss-lactam enzyme inhibitor and preparation method thereof 明治制果药业株式会社 2019-07-30 — — CN disclosed
US-10343438-B2 Heat-sensitive recording material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-07-09 — — US disclosed
CN-105859609-B Beta-lactamase inhibitor and preparation method thereof 明治制果药业株式会社 2019-04-09 — — CN disclosed
CN-109153635-A Neuropeptide S receptor (NPSR) agonist 研究三角协会 2019-01-04 — — CN disclosed
CN-108136044-A Imide-based proteolytic modulators and related methods of use 阿尔维纳斯股份有限公司 2018-06-08 — — CN disclosed
US-20170297355-A1 Heat-Sensitive Recording Material NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-10-19 — — US disclosed
EP-2755949-B1 FUNGICIDAL 4-SUBSTITUTED-3-{PHENYL[(HETEROCYCLYLMETHOXY)IMINO]METHYL}-1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER IP GMBH (DE) 2015-10-21 — — EP disclosed
US-9090600-B2 Fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadizol-5(4H)-one derivatives BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-07-28 — — US disclosed
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-11-27 — — US disclosed
CN-104136416-A Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO PHARM SOLUTIONS CO LTD 2014-11-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349848-A1 FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES CYP4X1, CYP4B1, CYP4Z1 LMNA 3306/4885HSD17B10 1293/4885FDPS 1595/4885
US-20170297355-A1 Heat-Sensitive Recording Material SCN1A, SCN3A, KCNN3 LMNA 881/4885HSD17B10 2248/4885FDPS 2898/4885
US-10343438-B2 Heat-sensitive recording material SCN1A, SCN3A, KCNN3 LMNA 881/4885HSD17B10 2248/4885FDPS 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.