Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452465 | 0.91 | KDM4C (0.39) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22453096 | 0.85 | KMT2A (0.39) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22452472 | 0.79 | DHODH (0.45) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22452596 | 0.78 | MTNR1A (0.38) | KMT2ALMNAMEN1 | |
| SCHEMBL22452451 | 0.75 | AKR1C3 (0.48) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22453050 | 0.75 | MEN1 (0.46) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22452445 | 0.75 | MEN1 (0.46) | KMT2ALMNAMEN1POLBMAPT | |
| SCHEMBL22453045 | 0.75 | SLC6A3 (0.40) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22452446 | 0.73 | KDM4C (0.46) | KDM4CKMT2ALMNAMEN1POLB | |
| SCHEMBL22453197 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |