Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453294 | 0.88 | KDM4E (0.41) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22453723 | 0.87 | CYP1A2 (0.35) | CYP1A2GRM5MAPTMEN1KMT2A | |
| SCHEMBL22453719 | 0.87 | CYP1A2 (0.37) | CYP1A2GRM5MAPTMEN1KMT2A | |
| SCHEMBL22453716 | 0.85 | PDCD1 (0.36) | CYP1A2GRM5MEN1KMT2AALDH1A1 | |
| SCHEMBL22453576 | 0.81 | CYP1A2 (0.40) | CYP1A2GRM5MAPTMEN1KMT2A | |
| SCHEMBL22453721 | 0.78 | MCHR1 (0.39) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL22453578 | 0.77 | MAPT (0.42) | CYP1A2MAPTGAAMEN1KMT2A | |
| SCHEMBL22453722 | 0.76 | ALDH1A1 (0.40) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22452820 | 0.76 | MCHR1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22452775 | 0.75 | KDM4E (0.42) | KMT2AALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |