Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18525809 | 0.93 | AR (0.44) | PRKCZARCYP19A1TDO2AKT1 | |
| SCHEMBL23731938 | 0.85 | PRKCZ (0.47) | PRKCZARCYP19A1TDO2AKT1 | |
| SCHEMBL444504 | 0.79 | PRKCZ (0.63) | PRKCZCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL8338721 | 0.78 | PRKCZ (0.58) | PRKCZARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL23555375 | 0.78 | PRKCZ (0.58) | PRKCZARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL13615233 | 0.78 | PRKCZ (0.53) | PRKCZARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL18891280 | 0.77 | CYP11B1 (0.69) | PRKCZCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL17691836 | 0.77 | PRKCZ (0.56) | PRKCZCYP11B2CYP11B1CYP19A1CYP17A1 | |
| SCHEMBL28302611 | 0.76 | PRKCZ (0.56) | PRKCZARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL28147640 | 0.76 | ESR1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10930859-B2 | Phenanthroquinazoline-core compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200303659-A1 | PHENANTHROQUINAZOLINE-CORE COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10930859-B2 | Phenanthroquinazoline-core compounds | TOP1, TOP2A, BICRA | PRKCZ 4381/4885AR 1911/4885CYP11B2 976/4885 |
| US-20200303659-A1 | PHENANTHROQUINAZOLINE-CORE COMPOUNDS | TOP1, TOP2A, BICRA | PRKCZ 4381/4885AR 1911/4885CYP11B2 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.