Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684452 | 1.00 | FFAR4 (0.45) | FFAR4FFAR1MAOBMAOACCR5 | |
| SCHEMBL22454501 | 0.84 | MAOB (0.58) | FFAR4FFAR1MAOBMAOAGAA | |
| SCHEMBL31658727 | 0.84 | NPC1 (0.54) | NPC1RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL31658734 | 0.81 | MAOB (0.42) | FFAR1MAOBMAOANPC1RAB9A | |
| SCHEMBL28921334 | 0.75 | MAOB (0.51) | FFAR4FFAR1MAOBMAOANPC1 | |
| SCHEMBL21513667 | 0.74 | LRRK2 (0.48) | NPC1RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL31658735 | 0.74 | NR3C1 (0.49) | FFAR4FFAR1MAOBNPC1RAB9A | |
| SCHEMBL2477376 | 0.74 | FFAR4 (0.73) | FFAR4FFAR1MAOBMAOANPC1 | |
| SCHEMBL2550366 | 0.73 | FFAR4 (0.49) | FFAR4FFAR1MAOBNPC1RAB9A | |
| SCHEMBL31496915 | 0.72 | FFAR1 (0.52) | FFAR4FFAR1MAOBMAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932923-B1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | UNIV CENTRAL CHINA NORMAL (CN) | 2023-05-03 | — | — | EP | disclosed |
| US-20220177477-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | Central China Normal University (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3932923-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | Central China Normal University (CN) | 2022-01-05 | — | — | EP | disclosed |
| WO-2020187291-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | 华中师范大学 | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177477-A1 | PYRAZOLOPYRIMIDINE COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREFOR | ITK, TKFC, WEE2 | FFAR4 294/4885FFAR1 451/4885MAOB 3217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.