Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 4/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357542 | 1.00 | NCF1 (0.51) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22441585 | 0.88 | NCF1 (0.55) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22455023 | 0.88 | NCF1 (0.46) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL31457622 | 0.88 | NCF1 (0.46) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22441459 | 0.80 | NCF1 (0.54) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22441462 | 0.80 | NCF1 (0.54) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22441556 | 0.80 | PDGFRB (0.49) | NCF1PDGFRBEHMT2EHMT1FLT3 | |
| SCHEMBL22455401 | 0.79 | NCF1 (0.56) | NCF1PDGFRBEHMT2EHMT1PDGFRA | |
| SCHEMBL24392505 | 0.79 | EHMT2 (0.49) | NCF1PDGFRBEHMT2EHMT1DRD2 | |
| SCHEMBL29589077 | 0.79 | EHMT2 (0.49) | NCF1PDGFRBEHMT2EHMT1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407729-B2 | Quinoline and quinazoline compounds and methods of use thereof | Stingray Therapeutics, Inc. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200299258-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2020-09-24 | — | — | US | disclosed |
| WO-2020190912-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299258-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | ENPP1, ENPP3, PDE7A | NCF1 283/4885PDGFRB 3543/4885EHMT2 2342/4885 |
| US-11407729-B2 | Quinoline and quinazoline compounds and methods of use thereof | ENPP1, ENPP3, PDE7A | NCF1 283/4885PDGFRB 3543/4885EHMT2 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.