⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22458038 | 1.00 | — | — | |
| SCHEMBL13523677 | 0.87 | ADRA2A (0.45) | — | |
| SCHEMBL12891558 | 0.87 | ADRA2A (0.45) | — | |
| SCHEMBL12891559 | 0.87 | ADRA2A (0.45) | — | |
| SCHEMBL8349907 | 0.76 | — | — | |
| SCHEMBL14025921 | 0.76 | — | — | |
| SCHEMBL6101909 | 0.75 | KEAP1 (0.39) | — | |
| SCHEMBL6899248 | 0.75 | GRIN2B (0.39) | — | |
| SCHEMBL14916238 | 0.74 | — | — | |
| SCHEMBL14914794 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219974-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
| US-11560388-B2 | Anthelmintic aza-benzothiophene and aza-benzofuran compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH | 2023-01-24 | — | — | US | disclosed |
| US-20200299304-A1 | ANTHELMINTIC AZA-BENZOTHIOPHENE AND AZA-BENZOFURAN COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2020-09-24 | — | — | US | disclosed |