Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21661749 | 0.92 | NAMPT (0.72) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL78108 | 0.91 | MAPT (0.53) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL8738157 | 0.89 | CYP17A1 (0.51) | POLBMEN1LMNAPKMAPEX1 | |
| Hydrochloric Acid SCHEMBL28891842 | 0.89 | MAPT (0.52) | POLBMEN1LMNAPKMAPEX1 | |
| Aminobenzoic Acid SCHEMBL6627812 | 0.88 | CYP17A1 (0.50) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL22461477 | 0.88 | NAMPT (0.52) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL8770870 | 0.88 | NAMPT (0.67) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL8773493 | 0.88 | NAMPT (0.67) | POLBMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL15648062 | 0.86 | NAMPT (0.62) | POLBMEN1LMNAPKMAPEX1 | |
| SCHEMBL21049533 | 0.86 | NAMPT (0.48) | POLBMEN1LMNAPKMAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | ANXA6, ANXA1, ANXA11 | POLB 1532/4885MEN1 2136/4885LMNA 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.